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Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial.

Detailed efficacy and safety data from PALOMA-1 will be submitted for presentation at the American Association for Cancer Research (AACR) Annual Meeting 2014 scheduled for April 5-9th in San Diego.

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We calculated that the analysis would require a sample of 300 patients per treatment group, which we increased to 375 to allow for a dropout rate of 20%.

Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial.

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Before-treatment and on-treatment values were compared using the Wilcoxon matched-pair signed-rank test.

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